WEEK 1 DISCUSSION

A. Definition : Microbiology
Microbiology is the science of microorganisms. Microbiology in relation to medicine is concerned mainly with the isolation and identification of the microorganisms that cause disease. Microbiology is the studied of microbes.


B. Classification of microbiology
1. Bacteria are single celled microbes. The cell structure is simpler than that of other organisms as there is no nucleus or membrane bound organelles. Instead their control centre containing the genetic information is contained in a single loop of DNA. Some bacteria have an extra circle of genetic material called a plasmid. The plasmid often contains genes that give the bacterium some advantage over other bacteria. For example it may contain a gene that makes the bacterium resistant to a certain antibiotic

Bacteria are classified into 5 groups according to their basic shapes: spherical (cocci), rod (bacilli), spiral (spirilla), comma (vibrios) or corkscrew (spirochaetes). They can exist as single cells, in pairs, chains or clusters.

2. Viruses are the smallest of all the microbes. They are said to be so small that 500 million rhinoviruses (which cause the common cold) could fit on to the head of a pin. They are unique because they are only alive and able to multiply inside the cells of other living things. The cell they multiply in is called the host cell.

A virus is made up of a core of genetic material, either DNA or RNA, surrounded by a protective coat called a capsid which is made up of protein. Sometimes the capsid is surrounded by an additional spikey coat called the envelope. Viruses are capable of latching onto host cells and getting inside them.

3. Fungi can be single celled or very complex multicellular organisms. They are found in just about any habitat but most live on the land, mainly in soil or on plant material rather than in sea or fresh water. A group called the decomposers grow in the soil or on dead plant matter where they play an important role in the cycling of carbon and other elements. Some are parasites of plants causing diseases such as mildews, rusts, scabs or canker. In crops fungal diseases can lead to significant monetary loss for the farmer. A very small number of fungi cause diseases in animals. In humans these include skin diseases such as athletes’ foot, ringworm and thrush.

4. Protozoa are single celled organisms. They come in many different shapes and sizes ranging from an Amoeba which can change its shape to Paramecium with its fixed shape and complex structure. They live in a wide variety of moist habitats including fresh water, marine environments and the soil.

Some are parasitic, which means they live in other plants and animals including humans, where they cause disease.Plasmodium, for example, causes malaria. They are motile and can move by:

Cilia - tiny hair like structures that cover the outside of the microbe. They beat in a regular continuous pattern like flexible oars.

• Flagella - long thread-like structures that extend from the cell surface. The flagella move in a whip-like motion that produces waves that propel the microbe around.
• Amoeboid movement - the organism moves by sending out pseudopodia, temporary protrusions that fill with cytoplasm that flows from the body of the cell.
  
  
  
  
  
  
  
  
  
  
  5. Algae can exist as single cells, an example of which is Chlamydomonas, or joined together in chains like Spirogyra or made up of many cells, for instance Rhodymenia (red seaweed).